APDA Research Funding 2007-08

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Centers for Advanced Research

Emory University School of Medicine
Atlanta, GA

Robert Wood Johnson Medical School
New Brunswick, NJ

Boston University School of Medicine
Boston, MA

University of Virginia Medical Center
Charlottesville, VA

Washington University Medical Center
St. Louis, MO

UCLA School of Medicine
Los Angeles, CA

University of Pittsburgh
Pittsburgh, PA

University of Alabama
Birmingham, AL

The University of Chicago
Chicago, IL

Cotzias Fellowships

Bradley Miller, MD, Ph.D.

University of Virginia,

Charlottesville, VA

Distribution and Metabolic Consequences of Mitochondrial DNA Deletions in Substantia Nigra and Cultured Cells

Joseph Savitt, MD, Ph.D.

Johns Hopkins Hospital,
Baltimore, MD

Conditional GDNF Receptor Knockout Mice:  Exploring the Role of GDNF in Dopaminergic Cell Development and Survival

Talene Yacoubian, MD, Ph.D.

The University of Alabama,
Birmingham, AL

Role of 14-3-3 Proteins in Alpha Synuclein Induced Neurotoxicity

CRoger Duvoisin, MD Grant

Andrei Alexandrescu, Ph.D.

University of Connecticut
Storrs, CT

Stability and Solvent Accessibility of Alpha-Synuclein Fibrils by NMR Hydrogen Exchange

James L. Roberts, MD, Ph.D.

University of Texas Health Science Center
San Antonio, TX

Molecular and Cellular Mechanisms of Estrogen Midiated Neuroprotection of Mesencephalic Dopaminergic Neurons

Jeffry Stock, Ph.D.

Princeton University
Princeton, NJ

Protein Phosphatase 2A Methylation as a Therapeutic Target for Parkinson’s Disease

Post-Doctoral Fellowships

Michelle Burack, MD, Ph.D.

University of Rochester
Rochester, NY

The Impact of Dopa-Induced Dyskinesia on Voluntary Motor Control in Patiens with Idiopathic Parkinson Disease

Joanne Clark, Ph.D.

Beth Israel Deaconess Medical Center
Boston, MA

Activation of PGC1a by P38MAPK; Potential Interference by A-synuclein

Clement Gautier, Ph.D.

Brigham and Women Hospital
Boston, MA

Investigation of Mitochondrial Functions in PINK 1 Knock Out Mice

Melissa Geddie, Ph.D.

Whitehead Institute for Biomedical Research, Cambridge, MA

Metal Ion Transport in Parkinson’s Disease

Keiichi Inoue, Ph.D.

Columbia University
New York, NY

Novel Animal Models of PD

Shilpa Iyer, Ph.D.

University of Virginia
Charlottesville, VA

In Vitro Characterization of Mechanisms of Mitochondrial DNA Homoplasmy

Nikolaus McFarland, MD, Ph.D.

Massachusetts General Hospital
Boston, MA

Alpha-Synuclein Phosphorylation and Toxicity in a Rat Model of Parkinson’s

Julie Tetzlaff, Ph.D.

Massachusetts General Hospital
Boston, MA

Therapeutic Reduction in Oligomeric Alpha-Synuclein Species

Shaji Theodore, Ph.D.

The University of Alabama
Birmingham, AL

A Novel Mode of Microglial Activation in a Mouse Model of Parkinson’s Disease

Harrison Walker, MD

The University of Alabama
Birmingham, AL

Clinical and Electrophysiological Investigation of Bilateral Effects of Unilateral Subthalamic Nucleus Deep Brain Stimulation

Allison Wright Willis, MD

Washington University
St. Louis, MO

Environment Heavy Metal Exposure and the Risk of PD:  A Community Health Study Using Geographical Information Systems

Research Grants

Asa Abeliovich, MD, Ph.D.

Columbia University
New York, NY

Novel Therapeutics for PD

Sarah Berman, MD, Ph.D.

University of Pittsburgh
Pittsburgh, PA

Exploration of Mitochondrial Dynamics in Models of Parkinson’s Disease

Guy Caldwell, Ph.D.

The University of Alabama
Tuscaloosa, AL

Identification and Functional Validation of Neuroprotective Genes Associated with Parkinson’s Disease

Sreeganga Chandra, Ph.D.

Yale University
New Haven, CT

Delineating the Physiological Functions of Synucleins

Sylvain Dore, Ph.D.

Johns Hopkins University School of Med.
Baltimore, MD

PGE2 EP1 Receptor Role in Parkinsonism

Ray Dorsey, MD

University of Rochester
Rochester, NY

A Guide to Improving the Impact of Parkinson Disease Research

Andrea Giuffrida, Ph.D.

University of Texas Health Science Center
San Antonio, TX

Neuroprotective Role of Cannabinoids in Parkinson’s Disease

Matthew Goldberg, Ph.D.

UT Southwestern Medical Center
Dallas, TX

Parkin, DJ-1 and Antioxidant-deficient Mouse Models of PD

Ming Guo, MD, Ph.D.

Brain Research Institute at UCLA
Los Angeles, CA

Characterization of the Function of a PINK 1 Binding Protein

Syed Iman, Ph.D.

University of Texas Health Science Center
San Antonio, TX

Evaluation of Stress-induced Tyrosine Kinase, c-Abl, as a Novel Therapeutic Target for Parkinson’s Disease

Steven Johnson, MD, Ph.D.

Portland VA Research Foundation
Portland, OR

Redox Regulation of NMDA Currents in Midbrain Dopamine Neurons

Andreas Kottmann, Ph.D.

Columbia University
New York, NY

On the Function of the Secreted Cell-Signaling Glycoprotein Sonic Hedgehog (Shh) Expressed by Mesencephalic Dopaminergic Neurons in the Postnatal Brain

Lawrence Kromer, Ph.D.

Georgetown University
Washington, DC

Role of Ephrins and Eph Receptors in Regulating Striatal Reinnervation by Dopaminergic Grafts

Matthew LaVoie, Ph.D.

Brigham and Women’s Hospital
Boston, MA

Dissecting the anti-Apoptotic Function of Parkin and the Impact of PD-Linked Parkin Mutations

Zhicheng Lin, Ph.D.

The McLean Hospital Corporation
Belmont, MA

Genetic Variation in Human Alpha-Synuclein Expression

Changwei Liu, Ph.D.

University of Colorado at Denver
Aurora, CO

Studying of the Role of the CHIP/Hsp70 E3 Ligase in Mediating the Ubiquitination of Serine 129 Phosphorylated Alpha-Synuclein

Nigel Maidment, Ph.D.

UCLA
Los Angeles, CA

Is VMAT Over-Expression Neuroprotective in Mammalian Alpha-Synuclein Models of PD

Anthony Nicholas, MD, Ph.D.

The University of Alabama
Birmingham, AL

Post-Translational Modifications of Histones in Levodopa-Induced Dyskinesia

Janis O’Donnell, Ph.D.

University of Alabama
Tuscaloosa, AL

In Vivo Analysis of the Role of 14-3-3 Zeta and Over-expression in Neurodegeneration in a Drosophilia PD Model

Owen Ross, Ph.D.

Mayo Clinic Jacksonville
Jacksonville, FL

Dysregulation of A-Synuclein Gene Expression in Parkinson’s Disease

Jay Schneider, Ph.D.

Thomas Jefferson University
Philadelphia, PA

Functional Significance of ALDH1 in Ventral Mesencephalic Dopamine Neurons

Lidia Serova, Ph.D.

New York Medical College
Valhalla, NY

Mechanism of Interaction Between Nicotine and Estradiol as Related to Tetrahydrobiopterin in Animal Model of Parkinson’s Disease

Paul Shaw, Ph.D.

Washington University
St. Louis, MO

Evaluating Protective Effects of Curcum in  Synuclein Pathology

Wanli Smith, MD, Ph.D.

Johns Hopkins University School of Med.
Baltimore, MD

Cytoplasmic LRRK2 Inclusion and Ubiquitination

Stephanie White, Ph.D.

University of California
Los Angeles, CA

Birdsong as a Model System for Parkinson’s Disease

Stephan Witt, Ph.D.

Louisiana State University Health Sci. Ctr.Shreveport, LA

Determining Why Phosphorylation of Alpha-Synuclein at Serine 129 Causes Toxicity

Baoji Xu, Ph.D.

Georgetown University
Washington, DC

Chronic Deprivation of TrkB Signaling Leads to Progressive and Selective Nigrostriatal Dopaminergic Degeneration

Jin Xu, Ph.D.

Caritas St. Elizabeth’s Medical Ctr.
Boston, MA

Functional Interplay Between DJ-1 and PGC-la

Cyrus Zabetian, MD, MS

Seattle Institute for Biomedical & Clinical
Research, Seattle, WA

Fine-mapping of a Chromosome 17q21 Region Associated with Parkinson’s Disease

Fu-Ming Zhou, Ph.D.

University of Tennessee
Memphis, TN

An Ultra-Short Dopamine Pathway:  Implications for Parkinson’s Disease

Wenbo Zhou, Ph.D.

University of Colorado Health Sci. Ctr.
Denver, CO

Testing Drugs that Upregulate DJ-1 in Mouse Models of Parkinson’s Disease